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Description

Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimers disease

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This neuroadaptive state can contribute to the development of tolerance, dependence, and withdrawal symptoms, further complicating the recovery process for individuals with AUDs (Bhandari et al

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Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

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doi: 10.3390/pathogens12050734 52 PavloviRBrodschneiderRGoesslerWStanisavljeviLVujiZZariNM

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Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency

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